This paper introduces a bioinspired transdermal patch technology that uses negative pressure, or suction, upon skin attachment to enhance drug delivery efficiency. It discusses how this technology can effectively deliver large-molecule drugs with less pain compared to traditional microneedle patches and explores various architectures and applications of this strategy.
Wet Bio-Adhesion Technology Using Flexible Micro-Cylinders Inspired by a Beetle’s Structure
This study introduces a technology that maintains high adhesion even in wet or moist environments by developing perforated micro-cylinders (PMMCs) inspired by the footpads of a diving beetle. Unlike conventional dry-adhesion techniques, this patch uses an oil-loadable...